HOming in on arteriovenous fistula survival.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18560362.
- Also identified by DOI 10.1038/ki.2008.127 and PMC identifier 2645071.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Vascular access failure is a major clinical problem for patients on hemodialysis, but therapeutic approaches aimed at improving arteriovenous fistula (AVF) dysfunction remain elusive. Using a murine AVF model, Juncos et al. demonstrate for the first time that the stress protein heme oxygenase-1 (HO-1) is induced in AVFs and that HO-1 is a critical determinant of AVF survival.
Medical subject headings
- Catheters, Indwelling
- Heme Oxygenase-1
- Renal Dialysis