In situ synthesis of hybrid nanocomposite with highly order arranged amorphous metallic copper nanoparticle in poly(2-hydroxyethyl methacrylate) and its potential for blood-contact uses.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18585991.
- Also identified by DOI 10.1016/j.actbio.2008.05.022.
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Abstract
A hybrid consisting of a highly ordered nanostructure of metallic Cu(0) nanoparticles embedded in a poly(2-hydroxyethyl methacrylate) (pHEMA) matrix was successfully synthesized by in situ photopolymerization, followed by in situ chemical reduction. The evolution of an ordered nanostructure of Cu(0) showing a nearly amorphous nature is discussed, and it is proposed that it is due to a coupling interaction between the Cu precursor and the unpaired O of the COOR group, associated with water molecules, among pHEMA molecules. The hybrids showed a negative surface charge and considerable improvement in blood compatibility compared to neat pHEMA and the widely used biomaterial polysulfonate.
Medical subject headings
- Copper
- Metal Nanoparticles
- Methacrylates
- Nanocomposites