The ongoing saga of sirtuins and aging.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18590685.
- Also identified by DOI 10.1016/j.cmet.2008.06.004.
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Abstract
Sirtuins are known to slow aging in simple eukaryotes; however, viewing mammalian sirtuins as antiaging proteins may be overly simplistic. In this issue of Cell Metabolism, Li et al. (2008) provide evidence that SirT1 has properties consistent with both pro- and antiaging functions in mice.
Medical subject headings
- Aging
- Sirtuins