Base behavior behind budding breasts: integrins and mammary stem cell activity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18593551.
- Also identified by DOI 10.1016/j.stem.2008.06.006.
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Abstract
In a recent Nature Cell Biology paper, Taddei et al. (2008) reveal that deletion of beta1 integrin from K5-expressing mammary epithelial basal cells specifically attenuates ductal stem cell activity, without dramatically altering the basal cell layer, or morphogenesis overall.
Medical subject headings
- Integrins
- Mammary Glands, Animal
- Stem Cells