Self-renewal made simple.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18593552.
- Also identified by DOI 10.1016/j.stem.2008.06.007.
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Abstract
Embryonic stem cells (ESCs) are prone to differentiation in culture, suggesting that maintenance of the pluripotent state must be actively induced. In a recent issue of Nature, Ying et al. (2008) use soluble small molecules to inhibit pro-differentiation signals and reveal ESC self-renewal as a default cell fate.
Medical subject headings
- Embryonic Stem Cells