Risk of neoplasia and malignancy in "dominant" thyroid swellings.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 1859949.
- Also identified by PMC identifier 1670270.
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Abstract
To determine the risk of neoplasia and malignancy in "dominant" thyroid swellings. Prospective analysis during six years. Thyroid clinic serving the Grampian region. 574 consecutive patients presenting with a discrete thyroid swelling, of whom 179 (31%) were classified clinically as having a dominant area of enlargement within a multinodular gland. After clinical and cytological assessment 77 dominant swellings were excised. Of the excised swellings, 45 were non-neoplastic and 32 neoplastic, including 11 malignant lesions. The minimum incidence of neoplasia and malignancy in all 179 dominant swellings was therefore 18% and 6% respectively. Dominant thyroid swellings should be regarded with greater clinical suspicion than has been traditional.
Medical subject headings
- Thyroid Diseases
- Thyroid Gland
- Thyroid Neoplasms