Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 18611160.
- Also identified by DOI 10.1086/590152.
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Abstract
The retrospective study of 34 patients with Hodgkin lymphoma-associated hemophagocytic syndrome led us to define this association as a specific disorder. Its characteristics are male predominance (male-to-female sex ratio, 3.3:1), immunodeficiency-like histological features (lymphocyte depletion, 45% of cases; mixed cellularity Hodgkin lymphoma subtype, 40%), and strong association with Epstein-Barr virus (94%).
Medical subject headings
- Epstein-Barr Virus Infections
- Herpesvirus 4, Human
- Hodgkin Disease
- Lymphohistiocytosis, Hemophagocytic