Diffusion-based tractography in neurological disorders: concepts, applications, and future developments.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18635020.
- Also identified by DOI 10.1016/S1474-4422(08)70163-7.
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Abstract
Diffusion-based tractography enables the graphical reconstruction of the white matter pathways in the brain and spinal cord of living humans. This technique has many potential clinical applications, including the investigation of stroke, multiple sclerosis, epilepsy, neurodegenerative diseases, and spinal cord disorders, and it enables hypotheses to be tested that could not previously be considered in living humans. This Review will outline the limitations of tractography, describe its current clinical applications in the most common neurological diseases, and highlight future opportunities.
Medical subject headings
- Diffusion Magnetic Resonance Imaging
- Image Processing, Computer-Assisted
- Nervous System Diseases