The efficacy of dexmedetomidine in patients with noninvasive ventilation: a preliminary study.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 18635484.
- Also identified by DOI 10.1213/ane.0b013e3181732dc2.
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Abstract
Agitation is associated with failure of noninvasive ventilation (NIV). We investigated the effect of dexmedetomidine in patients with NIV. This was a prospective clinical investigation in an intensive care unit. Dexmedetomidine was infused in 10 patients in whom NIV was difficult because of agitation. Ramsay and Richmond Agitation-Sedation Scale scores were maintained at 2.94 +/- 0.94 and -1.23 +/- 1.30, respectively. All patients were successfully weaned from NIV, and the respiratory state was not worsened. This study shows that dexmedetomidine is an effective sedative drug for patients with NIV.
Medical subject headings
- Dexmedetomidine
- Hypnotics and Sedatives
- Respiration, Artificial