PIGS: automatic prediction of antibody structures.

Marcatili, Paolo; Rosi, Alessandra; Tramontano, Anna · Bioinformatics · 2008

basic_science · Level V

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Abstract

We describe a web server for the automatic prediction of immunoglobulin variable domains based on the canonical structure model. The server is user-friendly and flexible. It allows the user to select the templates for the frameworks and the loops using different strategies. The final output is a full-fledged 3D model of the variable domains of the target immunoglobulin. The server is openly accessible to academic users at the address: http://arianna.bio.uniroma1.it/pigs. It does not require registration and there is no limit to the number of sequences that can be submitted.

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