Interstitial high-dose-rate-brachytherapy in advanced esthesioneuroblastoma.

Tselis, Nikolaos; Heyd, Reinhard; Baghi, Mehran; Zamboglou, Nikolaos · Laryngoscope · 2008

case_report · Level V

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Abstract

Esthesioneuroblastoma is a rare neuroectodermal tumor of the nasal vault with an aggressive biological behavior that is characterized by local recurrence, atypical distant metastasis, and poor long-term prognosis. The treatment regimen consists of surgical resection, radiation therapy, and chemotherapy in various, mainly stage-dependent, combinations. We report two cases of primary metastatic and locally recurrent disease, which were treated with computed tomography-guided interstitial high-dose-rate brachytherapy in palliative and curative intent, respectively. Computed tomography-guided interstitial high-dose-rate brachytherapy should be considered as a feasible treatment option for advanced esthesioneuroblastoma.

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