A histone code for chromatin assembly.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18662534.
- Also identified by DOI 10.1016/j.cell.2008.07.007.
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Abstract
In this issue, two papers implicate histone H3 lysine 56 acetylation in histone deposition in chromatin. Li et al. (2008) show that acetylation of H3K56 promotes S phase chromatin assembly that is mediated by the histone chaperones CAF-1 and Rtt106. Chen et al. (2008) establish that the acetylation mark promotes chromatin reassembly following DNA double-strand break repair.
Medical subject headings
- Chromatin Assembly and Disassembly
- Histone Code
- Histones
- Saccharomyces cerevisiae