A PASport to cellular proliferation.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18662535.
- Also identified by DOI 10.1016/j.cell.2008.07.003.
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Abstract
The use of alternative polyadenylation sites produces mRNA isoforms with different 3' untranslated regions. A recent report in Science (Sandberg et al., 2008) suggests that alternative polyadenylation is connected to microRNA-mediated regulation of gene expression as part of a global program for cellular proliferation.
Medical subject headings
- 3' Untranslated Regions
- Cell Proliferation
- Gene Expression Regulation
- Polyadenylation