Cdc14B and APC/C tackle DNA damage.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18662536.
- Also identified by DOI 10.1016/j.cell.2008.07.004.
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Abstract
Mitotic exit in budding yeast is regulated by the proteins Cdc14, APC/C(Cdh1), and Plk1. In this issue, Bassermann and colleagues (2008) show that this network of proteins has been rewired in human cells to control the cell cycle in response to DNA damage.
Medical subject headings
- Cell Cycle
- Cell Cycle Proteins
- DNA Damage
- Dual-Specificity Phosphatases
- Ubiquitin-Protein Ligase Complexes