Genetic modification-free reprogramming to induced pluripotent cells: fantasy or reality?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18682230.
- Also identified by DOI 10.1016/j.stem.2008.07.005.
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Abstract
Significant development in the reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) has been achieved by retroviral infection of defined genes. Several recent reports, including one in this issue of Cell Stem Cell (Marson et al., 2008), have started to replace these genetic changes with specific chemical stimulation.
Medical subject headings
- Cellular Reprogramming
- Epigenesis, Genetic
- Pluripotent Stem Cells
- Signal Transduction