Lowering HbA1c in type 2 diabetics results in reduced risk of coronary heart disease and all-cause mortality.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18684420.
- Also identified by DOI 10.1016/j.pcd.2007.12.004.
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Abstract
To assess to which extent lowering the level of HbA1c influences the 10-year risk of coronary heart disease (CHD) and all-cause mortality in patients with type 2 diabetes mellitus. A literature search in Pubmed and Embase was performed, and the absolute risks in the results of the relevant and valid studies compared. Each study shows that with a decreasing percentage of HbA1c, both the risk of developing CHD and the risk of mortality decrease. Lowering HbA1c in type 2 diabetics decreases the absolute risk of developing CHD by 5-17%, as well as decreasing all-cause mortality by 6-15%.
Medical subject headings
- Coronary Disease
- Diabetes Mellitus, Type 2
- Diabetic Angiopathies
- Glycated Hemoglobin