Programming DNA tube circumferences.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18687961.
- Also identified by DOI 10.1126/science.1157312.
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Abstract
Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.
Medical subject headings
- DNA
- DNA, Single-Stranded
- Nanotechnology
- Nucleic Acid Conformation