Nanomechanical resonance spectroscopy: a novel route to ultrasensitive label-free detection.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18707177.
- Also identified by DOI 10.1021/nl0808278.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We propose a new chemical detection technique in which an analyte's vibrational frequencies are interrogated directly using an array of nanomechanical resonators. This "nanomechanical resonance spectroscopy" (NRS) could permit label-free chemical detection, combining the high sensitivity of nanomechanical approaches with the high selectivity of traditional spectroscopy. A computational proof of principle is presented, demonstrating the central concept: exploiting resonant exchange of vibrational energy for chemical identification. Guidelines for experimental realization of NRS are discussed.