Current treatment concepts for neuromas-in-continuity.

Mavrogenis, Andreas F; Pavlakis, Kitty; Stamatoukou, Anna; Papagelopoulos, Panayiotis J; Theoharis, Stamatios; Zoubos, Aristidis B; Zhang, Zijie; Soucacos, Panayotis N · Injury · 2008

review · Level V

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Abstract

A neuroma-in-continuity is a neuroma that results from failure of the regenerating nerve growth cone to reach peripheral targets. It occurs within an intact nerve in response to internally damaged fascicles, resulting in a distal portion of the nerve that no longer functions properly. Management of neuromas-in-continuity is challenging. Chemical methods, and microsurgical techniques including fascicular ligation, and burying into muscle and bone have been reported to prevent neuroma-in-continuity formation. The purpose of this article is to present novel techniques for neuroma-in-continuity management, and to discuss the related literature.

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