cneViewer: a database of conserved non-coding elements for studies of tissue-specific gene regulation.
Where this comes from
- Record sourced from PubMed, PMID 18718943.
- Also identified by DOI 10.1093/bioinformatics/btn443 and PMC identifier 2562007.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
There are thousands of strongly conserved non-coding elements (CNEs) in vertebrate genomes, and their functions remain largely unknown. However, without biologically relevant criteria for prioritizing them, selecting a particular CNE sequences to study can be haphazard. To address this problem, we present cneViewer-a database and webtool that systematizes information on conserved non-coding DNA elements in zebrafish. A key feature here is the ability to search for CNEs that may be relevant to tissue-specific gene regulation, based on known developmental expression patterns of nearby genes. cneViewer provides this and other organizing features that significantly facilitate experimental design and CNE analysis.
Medical subject headings
- Computational Biology
- Databases, Genetic
- Gene Expression Regulation
- Regulatory Sequences, Nucleic Acid
- Zebrafish