AMIN domains have a predicted role in localization of diverse periplasmic protein complexes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18723522.
- Also identified by DOI 10.1093/bioinformatics/btn449 and PMC identifier 2572700.
- Licence recorded as CC BY-NC.
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Abstract
We describe AMIN (Amidase N-terminal domain), a novel protein domain found specifically in bacterial periplasmic proteins. AMIN domains are widely distributed among peptidoglycan hydrolases and transporter protein families. Based on experimental data, contextual information and phyletic profiles, we suggest that AMIN domains mediate the targeting of periplasmic or extracellular proteins to specific regions of the bacterial envelope.
Medical subject headings
- Bacterial Proteins
- Periplasmic Proteins