Relationship of pneumocystis antibody response to severity of chronic obstructive pulmonary disease.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 18724825.
- Also identified by DOI 10.1086/591701 and PMC identifier 2602869.
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Abstract
Pneumocystis colonization has been associated with severity of chronic obstructive pulmonary disease (COPD). The relationship of Pneumocystis antibody status to COPD severity has not been investigated, but antibody levels might relate to both colonization susceptibility and COPD progression. We investigated anti-Pneumocystis antibody titers and airway obstruction in a cohort of patients with COPD. Undetectable anti-Pneumocystis antibody titer was an independent predictor of more-severe airway obstruction, although use of inhaled corticosteroids is a possible confounder of this effect.
Medical subject headings
- Antibodies, Fungal
- Pneumocystis carinii
- Pulmonary Disease, Chronic Obstructive
- Serine Endopeptidases