Proteomics joins the search for microRNA targets.

Grosshans, Helge; Filipowicz, Witold · Cell · 2008

basic_science · Level V

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Abstract

Two recent studies published in Nature (Baek et al. 2008; Selbach et al., 2008) analyze changes in the proteome in response to individual microRNAs (miRNAs). This approach is a powerful means to identify miRNA targets and to quantify the contribution of translational repression to posttranscriptional gene silencing by miRNAs.

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