Gle1 does double duty.

Kutay, Ulrike; Panse, Vikram Govind · Cell · 2008

basic_science · Level V

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Abstract

During nuclear export, Gle1 (the nuclear-pore-associated mRNA export factor) activates the DEAD-box protein Dbp5 to remodel exported mRNA-protein complexes on the cytoplasmic face of the nuclear pore complex. In this issue, Bolger et al. (2008) now report additional roles for Gle1 in translation initiation and termination.

Medical subject headings