Localized pemphigoid shares the same target antigen as bullous pemphigoid.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 1873209.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A case of localized pemphigoid is described in which the lesions were only on the lower legs. Immunoblotting of the patients' serum reacted with a 240-kDa polypeptide identical to one of the bullous pemphigoid antigens. IgG1 was detected in the lesional skin and IgG1 and IgG4 in the patient's serum. These observations suggest that the immunopathological mechanisms in the blister formation in localized pemphigoid are similar to those found in more widespread bullous pemphigoid.
Medical subject headings
- Antigens
- Immunoglobulin G
- Pemphigoid, Bullous
- Skin