Water soluble single-walled carbon nanotubes inhibit stimulated endocytosis in neurons.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18759491.
- Also identified by DOI 10.1021/nl8017912 and PMC identifier 2637913.
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Abstract
We report the use of chemically functionalized water soluble single-walled carbon nanotube (SWNT) graft copolymers to inhibit endocytosis. The graft copolymers were prepared by the functionalization of SWNTs with polyethylene glycol. When added to the culturing medium, these functionalized water soluble SWNTs were able to increase the length of various neuronal processes, neurites, as previously reported. Here we have determined that SWNTs are able to block stimulated membrane endocytosis in neurons, which could then explain the previously noted extended neurite length.
Medical subject headings
- Endocytosis
- Nanotechnology
- Nanotubes, Carbon
- Neurons
- Water