PI3K enters beta-testing.

Shaywitz, Adam J; Courtney, Kevin D; Patnaik, Akash; Cantley, Lewis C · Cell Metab · 2008

review · Level V

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Abstract

Phosphoinositide-3-OH kinases (PI3K) are critical regulators of cell metabolism, growth, and survival. In a recent publication in Nature, Jia et al. (2008) identify specific functions of the p110beta isoform of PI3K in glucose metabolism, cellular proliferation, and tumorigenesis.

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