Subependymoma with rhabdomyosarcomatous differentiation: report of a case and literature review.

Tomlinson, F H; Scheithauer, B W; Kelly, P J; Forbes, G S · Neurosurgery · 1991

case_report · Level V

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Abstract

A unique gliomesenchymal neoplasm, consisting of a subependymoma, a form of low-grade glioma, and a rhabdomyosarcoma, is described. It arose and recurred in the brain stem of a 52-year-old man. Immunohistochemical studies demonstrated the presence of a neuroectodermal marker S-100 protein within some sarcoma cells. The occurrence of this rare tumor supports the concept that striated muscle may derive from a neuroectodermal precursor lesion.

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