Cancer cell metabolism: Warburg and beyond.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18775299.
- Also identified by DOI 10.1016/j.cell.2008.08.021.
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Abstract
Described decades ago, the Warburg effect of aerobic glycolysis is a key metabolic hallmark of cancer, yet its significance remains unclear. In this Essay, we re-examine the Warburg effect and establish a framework for understanding its contribution to the altered metabolism of cancer cells.
Medical subject headings
- Biosynthetic Pathways
- Energy Metabolism
- Neoplasms