Unresolved ER Stress Inflames the Intestine.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18775305.
- Also identified by DOI 10.1016/j.cell.2008.08.023.
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Abstract
Intestinal epithelial cells interact with both microbes in the gut lumen and host immune cells. In this issue, Kaser et al. (2008) link a key mediator of endoplasmic reticulum stress, the protein XBP1, with survival of intestinal secretory epithelial cells and inflammatory bowel disease.
Medical subject headings
- DNA-Binding Proteins
- Endoplasmic Reticulum
- Inflammatory Bowel Diseases
- Intestinal Mucosa
- Transcription Factors