Stem cells for kidney repair: useful tool for acute renal failure?
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18794815.
- Also identified by DOI 10.1038/ki.2008.327.
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Abstract
Several cell types isolated from adult tissues have been reported to differentiate into mature kidney cells that may participate in renal repair after systemic administration. Chen et al. report that local mesenchymal stem cells derived from adult mouse kidneys are another source of cells with similar properties. Although these cells have the potential to differentiate into endothelial-lineage cell types, their therapeutic benefit to the ischemic kidney is mainly via the production of renoprotective factors.
Medical subject headings
- Acute Kidney Injury
- Regeneration
- Stem Cell Transplantation