An active feedback system for isotonic studies of smooth muscle.

Sabourin, P J; Kingma, Y J; Bowes, K L · IEEE Trans Biomed Eng · 1991

basic_science · Level V

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Abstract

A feedback system used to perform isotonic studies of smooth muscle is presented. This system is capable of applying a constant force to muscle samples regardless of their contractile activities. The force applied to the tissue is controlled using a proportional integral control system that drives a linear motor. The device is integrated into a sucrose gap tissue bath apparatus where measurements of displacement and electrical activity are also possible. The frequency of canine colonic smooth-muscle electrical oscillations is positively related to applied force.

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