Allograft and bone morphogenetic proteins: an overview.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 18804571.
- Also identified by DOI 10.1016/S0020-1383(08)70013-5.
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Abstract
Allograft is frequently used in orthopaedic and trauma surgery. On top of safety issues its biological activity is limited also due to processing. Consequently, the combination of allograft with osteoinductive substances may increase its effectiveness and decrease failure rates. In particular Bone Morphogenetic Proteins (BMPs) seem to be a promising partner for clinical applications. This overview focuses on the combined application of allograft/BMPs. Current points of view from available literature are summarized.
Medical subject headings
- Bone Morphogenetic Proteins
- Bone Transplantation
- Fractures, Bone