Putting a notch in our understanding of nuclear migration.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18805082.
- Also identified by DOI 10.1016/j.cell.2008.09.007.
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Abstract
The nuclei of progenitor cells in developing neural epithelia change their position during the cell cycle through a process called interkinetic nuclear migration. Del Bene et al. (2008) report that defects in the machinery controlling this process lead to altered exposure to Notch signals and systemic effects on neurogenesis in the retina.
Medical subject headings
- Cell Nucleus
- Receptors, Notch
- Retina