Elevated medial-frontal cerebral blood flow in obsessive-compulsive patients: a SPECT study.

Machlin, S R; Harris, G J; Pearlson, G D; Hoehn-Saric, R; Jeffery, P; Camargo, E E · Am J Psychiatry · 1991

case_control · Level III

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Abstract

Regional cerebral blood flow was measured with single photon emission computed tomography in 10 obsessive-compulsive patients and eight comparison subjects. The patients had a significantly higher ratio of medial-frontal to whole cortex blood flow; this was unrelated to symptom severity but was correlated negatively with anxiety. No differences in orbital-frontal blood flow were found.

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