Mass spectrometry-based proteomics: principles, perspectives, and challenges.
basic_science · Level V
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Abstract
Mass spectrometry-based proteomics is a modern and rapidly developing methodology for qualitative and quantitative characterization of proteins and their posttranslational modification, subcellular localization, and interaction partners. It enables characterization of entire proteomes with unprecedented sensitivity and precision, providing platforms for identification of biomarkers and drug targets.
Medical subject headings
- Mass Spectrometry
- Proteomics