Occupation, gender, race, and lung cancer.

Amr, Sania; Wolpert, Beverly; Loffredo, Christopher A; Zheng, Yun-Ling; Shields, Peter G; Jones, Raymond; Harris, Curtis C · J Occup Environ Med · 2008

case_control · Level III

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Abstract

To examine associations between occupation and lung cancer by gender and race. We used data from the Maryland Lung Cancer Study of nonsmall cell lung carcinoma (NSCLC), a multicenter case control study, to estimate odds ratios (ORs) of NSCLC in different occupations. After adjusting for smoking, environmental tobacco smoke, and other covariates, NSCLC ORs among women but not men were elevated in clerical-sales, service, and transportation-material handling occupations; ORs were significantly increased in all three categories (OR [95% confidence interval]: 4.07 [1.44 to 11.48]; 5.15 [1.62 to 16.34]; 7.82 [1.08 to 56.25], respectively), among black women, but only in transportation-material handling occupations (OR [95% confidence interval[: 3.43 [1.02 to 11.50]) among white women. Women, especially black women, in certain occupations had increased NSCLC ORs.

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