OMA-gosh, where's that TAF?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18854150.
- Also identified by DOI 10.1016/j.cell.2008.09.021.
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Abstract
How transcription is silenced in early embryos has long been a mystery. In this issue, Guven-Ozkan et al. (2008) report that transcriptional repression during worm embryogenesis is mediated through sequestration of the general transcription factor TAF-4 and is regulated by mechanisms that orchestrate the transition between maternal and zygotic gene expression.
Medical subject headings
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Carrier Proteins
- Gene Silencing
- Transcription Factors