Ellipsometric studies of plasma protein adsorption on membrane polymers for blood purification.

Mandenius, C F; Ljunggren, L · Biomaterials · 1991

basic_science · Level V

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Abstract

Description of ellipsometric studies on absorption of the human plasma proteins; albumin (HSA), immunoglobulin G (IgG) and fibrinogen (FGN) to polymer surfaces of polyamide, polysulphone, polyetherpolycarbonate and polyacrylonitrile copolymer. Thin layers of the polymers (20-30 nm) were cast onto silicon dioxide/silicon wafers by a spin-coating procedure. The variations observed in surface concentration and adsorption time of the proteins were significant in all four polymers investigated.

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