Increased detectability of plasma HIV-1 RNA after introduction of a new assay and altered specimen-processing procedures.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 18922071.
- Also identified by DOI 10.1086/592693 and PMC identifier 2605467.
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Abstract
After changes to assay and specimen-processing methods, plasma human immunodeficiency virus type 1 (HIV-1) RNA was frequently detectable in patients who previously had well-suppressed HIV-1 RNA levels. This artifact is attributable to shipping frozen plasma in primary plasma preparation tubes and is not caused by the HIV-1 RNA detection assay; it can be avoided by shipping plasma in a secondary tube.
Medical subject headings
- HIV Infections
- HIV-1
- RNA, Viral
- Specimen Handling
- Viral Load