Endoscopic transnasal decompression for management of basilar invagination in osteogenesis imperfecta.

Hansen, Mitchell A; da Cruz, Melville J; Owler, Brian K · J Neurosurg Spine · 2008

case_report · Level V

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Abstract

Osteogenesis imperfecta (OI) is a disorder of bone development caused by a genetic dysfunction of collagen synthesis. Basilar invagination (BI) is an uncommon but serious complication of OI. Brainstem decompression in OI is undertaken in certain circumstances. Transoral-transpalatopharyngeal ventral decompression with posterior occipitocervical fusion has become the treatment of choice when required. This technical note outlines a novel endoscopic transnasal approach for ventral decompression. The literature is reviewed and a strategy for the management of BI in patients with OI is outlined.

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