Using notches to track mammary epithelial cell homeostasis.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18940725.
- Also identified by DOI 10.1016/j.stem.2008.09.014.
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Abstract
Notch signals mediate a wide range of activities in development and cancer. A report in this issue of Cell Stem Cell (Bouras et al., 2008) demonstrates that Notch serves as a switch that controls cell fate and tissue homeostasis in mammary epithelium.
Medical subject headings
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Cell Differentiation
- Cell Lineage
- Epithelial Cells
- Mammary Glands, Animal
- Receptor, Notch1
- Signal Transduction