Myeloproliferative disorder by TKO.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18940726.
- Also identified by DOI 10.1016/j.stem.2008.09.008.
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Abstract
In this issue of Cell Stem Cell, Viatour et al. (2008) delete all three members of the retinoblastoma tumor suppressor gene family in hematopoietic stem cells, resulting in a myeloproliferative disorder. The disease was cell autonomous and resulted from alterations in the primitive hematopoietic cells.
Medical subject headings
- Cell Differentiation
- Cell Lineage
- Hematopoietic Stem Cells
- Retinoblastoma Protein
- Retinoblastoma-Like Protein p107
- Retinoblastoma-Like Protein p130