Apoptosis: Stabbed in the BAX.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18948940.
- Also identified by DOI 10.1038/4551047a and PMC identifier 3242476.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Apoptotic cell death is an intricate and highly regulated process. To initiate apoptosis, the protein BIM binds to a hitherto unrecognized site on the BAX protein to trigger permeabilization of the outer mitochondrial membrane.
Medical subject headings
- Apoptosis
- Apoptosis Regulatory Proteins
- Membrane Proteins
- Mitochondrial Membranes
- Proto-Oncogene Proteins
- bcl-2-Associated X Protein