Matriderm versus Integra: a comparative experimental study.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18951720.
- Also identified by DOI 10.1016/j.burns.2008.07.018.
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Abstract
To compare engraftment rates and vascularisation in a rat model using either Integra Artificial Skin or Matriderm. Matriderm and the dermal part of Integra were compared in a two-step procedure including matrix implantation and subsequent epidermal grafting. Neonatal rat epidermis was used as coverage to test for rapid and complete take. Efficiency and quality of vascularisation expressed by take rate of epidermis, and thickness of resulting neodermis, were identical for both matrices. This first comparison of Matriderm with Integra in a rat model revealed no major differences in engraftment rates or vascularisation.
Medical subject headings
- Chondroitin Sulfates
- Collagen
- Elastin
- Skin