A case of granulomatous hepatitis after intravesical bacillus Calmette-Guerin administration.

Graziano, D A; Jacobs, D; Lozano, R G; Buck, R L · J Urol · 1991

case_report · Level V

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Abstract

A 61-year-old man received intravesical bacillus Calmette-Guerin (BCG) as treatment for superficial bladder carcinoma. High spiking relapsing fevers began 39 days after the initial treatment. A liver biopsy revealed noncaseating granuloma. Deoxyribonucleic acid hybridization of the bone marrow was positive for Mycobacterium tuberculosis complex. Pressure exerted to instill the BCG may have favored dissemination.

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