Develop-WNTs in somatic cell reprogramming.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 18983957.
- Also identified by DOI 10.1016/j.stem.2008.10.011.
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Abstract
Two manuscripts published recently in Cell Stem Cell (Lluis et al., 2008 [this issue]; Marson et al., 2008) show that Wnt-beta-catenin signaling stimulates nuclear reprogramming. These two studies, using distinct reprogramming methods, offer insights into the mechanisms underlying acquisition and maintenance of pluripotency.
Medical subject headings
- Cellular Reprogramming
- Gene Expression Regulation, Developmental
- Pluripotent Stem Cells
- Wnt Proteins
- beta Catenin