Role for adhesion molecules in the spermatogonial stem cell niche.

de Rooij, Dirk G; Repping, S; van Pelt, Ans M M · Cell Stem Cell · 2008

editorial · Level V

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Abstract

In this issue of Cell Stem Cell, Kanatsu-Shinohara et al. (2008) show that beta1-integrin participates in normal spermatogenesis and is required for spermatogonial stem cell (SSC) homing to the basal membrane niche. The methodology used provides a powerful tool to study the role of other factors in niche-SSC interactions.

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