Heterogeneity of embryonic and adult stem cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18983963.
- Also identified by DOI 10.1016/j.stem.2008.10.007.
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Abstract
New studies suggest that stem cells of embryonic, neural, and hematopoietic origin are heterogeneous, with cells moving between two or more metastable states. These cell states show a bias in their differentiation potential and correlate with specific patterns of transcription factor expression and chromatin modifications.
Medical subject headings
- Adult Stem Cells
- Cell Lineage
- Embryonic Stem Cells
- Epigenesis, Genetic
- Gene Expression Regulation, Developmental
- Hematopoietic Stem Cells