Autism and brain development.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 18984148.
- Also identified by DOI 10.1016/j.cell.2008.10.015 and PMC identifier 2701104.
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Abstract
Genetic studies are refining our understanding of neurodevelopmental mechanisms in autism. Some autism-related mutations appear to disrupt genes regulated by neuronal activity, which are especially important in development of the postnatal nervous system. Gene replacement studies in mice indicate that the developmental window to ameliorate symptoms may be wider than previously anticipated.
Medical subject headings
- Autistic Disorder
- Brain